Stem cells are of particular interest for researchers because they begin as undifferentiated and differentiate into specialized cells over time. Significant research has been carried out on stem cells in recent years, exploring how they can help with therapeutics. Analyzing them with a particle shape and size analyzer can help with this.
Particle Insight as a Particle Shape and Size Analyzer
The Particle Insight uses dynamic image analysis to analyze particles and has been used for stem cell analysis by quantifying them by size and shape. This high-speed particle shape and size analyzer provides quantification and differentiation between identified particles such as the cells themselves and debris that has been suspended in the fluid.
Measuring concentration is a critical aspect of this application allowing for accurate differentiation between cells and debris. It is also crucial to know the concentration of each identified population in the sample to learn more about the contents.
The Importance of Shape Analysis
The capacity to keep pictures of the particles measured by the particle shape and size analyzer offers objective evidence of the samples. With stem cell measurements it is important to investigate the size and opacity information to learn about the viability. It is also important to look at other shape parameters such as circularity and concentration information.
Why Choose Particle Insight as Your Particle Shape and Size Analyzer
Size, shape, and concentration information are extremely helpful when researching stem cell science. The Particle Insight has been used to investigate stem cells and how they elongate as they move towards apoptosis.
Particle shape and size analyzers such as The Particle Insight quantify and calculate data in real-time, storing data including thumbnail images. These thumbnail images allow for a visual presentation to enhance understanding of the particles in the suspension.
Benefits offered by Particle Insight
The Particle Insight particle shape and size analyzer from Vision Analytical is capable of enumeration. This means it can be used to determine both the concentration and percentage of small or dark particles in the entire population.
Particle Insight can be used with software tools to obtain more in-depth information. This could then be used to perform a correlation between the size of the cell and its opacity. The correlation function could also be used to learn whether particles get rougher as they get larger and many other characteristics.
The particle classification function of this particle shape and size analyzer allows the user to obtain a deeper analysis of sub-populations of the sample. These particles can be sorted into different classes using their shape differences and this can identify which percent of each population is present in the sample.
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The Particle Insight uses dynamic image analysis to provide more information than traditional cell counters and particle size analyzers.
